Nonetheless, chemicals with these effects shall be classified as reproductive toxicants.
Some reproductive toxic effects cannot be clearly assigned to either impairment of sexual function and fertility or to developmental toxicity. Reproductive toxicity includes adverse effects on sexual function and fertility in adult males and females, as well as adverse effects on development of the offspring. Oxidizing gas means any gas which may, generally by providing oxygen, cause or contribute to the combustion of other material more than air does.Īn oxidizing liquid or solid is a substance which, while not necessarily combustible, may, generally by yielding oxygen, cause or contribute to the combustion of other material.Ī pyrophoric liquid is a liquid which, even in small quantities, is liable to ignite within five minutes after coming into contact with air.Ī pyrophoric solid is a solid which, even in small quantities, is liable to ignite within five minutes after coming into contact with air. The term mutagenic and mutagen will be used for agents giving rise to an increased occurrence of mutations in populations of cells and/or organisms.Īn organic peroxide is an organic liquid or solid which contains the bivalent -0-0- structure and may be considered a derivative of hydrogen peroxide, where one or both of the hydrogen atoms have been replaced by organic radicals. The term mutation applies both to heritable genetic changes that may be manifested at the phenotypic level and to the underlying DNA modifications when known (including, for example, specific base pair changes and chromosomal translocations). Aerosols are classified as flammable if they contain any component classified as flammable according to the GHS criteria for flammable liquids, flammable gases, or flammable solids.Ī mutation is defined as a permanent change in the amount or structure of the genetic material in a cell.
The container is fitted with a release device allowing the contents to be ejected as solid or liquid particles in suspension in a gas, as a foam, paste or powder or in a liquid or gaseous state. Readily combustible solids are powdered,granular, or pasty substances which are dangerous if they can be easily ignited by brief contact with an ignition source, such as a burning match, and if the flame spreads rapidly.Īerosols are any gas compressed, liquefied or dissolved under pressure within a non-refillable container made of metal, glass or plastic, with or without a liquid, paste or powder. Flammable solids are solids that are readily combustible, or may cause or contribute to fire through friction. Flammable liquid means a liquid having a flash point of not more than 93 ☌. Pyrotechnic chemicals are included even when they do not evolve gases.įlammable gas means a gas having a flammable range in air at 20 ☌ and a standard pressure of 101.3 kPa. Substances and mixtures which have induced benign and malignant tumors in wellperformed experimental studies on animals are considered also to be presumed or suspected human carcinogens unless there is strong evidence that the mechanism of tumor formation is not relevant for humans.Ī substance or a mixture that by chemical action will materially damage, or even destroy, metals is termed ”corrosive to metal.”Īn explosive chemical is a solid or liquid chemical which is in itself capable by chemical reaction of producing gas at such a temperature and pressure and at such a speed as to cause damage to the surroundings. Acute toxicity refers to those adverse effects occurring following oral or dermal administration of a single dose of a substance, or multiple doses given within 24 hours, or an inhalation exposure of 4 hoursĪspiration means the entry of a liquid or solid chemical directly through the oral or nasal cavity, or indirectly from vomiting, into the trachea and lower respiratory system.Ĭarcinogen means a substance or a mixture of substances which induce cancer or increase its incidence.
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